Slideroll

PUBLICATIONS & CONGRES


1.       Khan, N.A. and Hasan, S.S. (1984). Effects of a mild dose of X-irradiation on rats under stress.
Strahlentherapie.  160 : 194 - 199.

2.      Khan, N.A. and Hasan, S.S. (1984). Effects of cannabis hemp (Hashish) on normal and rats subjected to psychological stress. Proc. Ind. Acad. Sci. 93 : 121 - 129.

3.       Khan, N.A. (1985). A preliminary study of D. alba  (seeds) extract on normal and stressed rats. Ind. J. Physiol. Allied Sci. 39 : 100 - 107.

4.       Khan, N.A. (1986). Synthesis of C6 by liver. Ind. J. Physiol. Allied Sci. 110 : 113 - 114.

5.       Khan, N.A. (1986). Impact of marijuana smoke inhalation on normal  and stressed rats. Ind. J. Pharmacol.  18 : 215 - 222.

6.       Khan, N.A. (1987). Effects of Datura and diazepam on rat brain enzymes. Ind. J. Anim. Sci. 57 : 1074 -1077.

7.       Khan, N.A. and Kalra, V. (1988). Urinary 5-HIAA and VMA and their relationship with immunoregulatory cells in stress administered subjects. Arch. Immunol. Therap. Exp. 36 : 717 - 721.

8.       Khan, N.A. and Sotelo, J. (1988). Treatment of B-cell lymphoma with monoclonal anti-idiotype antibody. Cancer J.  2 : 177 - 178.

9.       Khan, N.A. and Ramos, C. (1988). Production of a monoclonal anti-idiotype antibody using mouse myeloma and human lymphoid hybridoma. Cancer J.  2 :  201 - 203.

10.    Khan, N.A., Quemener V.  and  Moulinoux,  J.Ph.  (1989). Characterization   of   Na+ - dependent and System A independent polyamine transport in normal human erythrocytes. Biochem. Arch. 5 : 161 - 166.

11.    Khan, N.A., Guevara, P. and Sotelo J. (1989). Effect   of  in  vitro    lactic  acidosis  on CNS cultured neurons. Path. Biol.  37 : 725 - 729.

12.    Khan, N.A., Quemener V. and Moulinoux, J.Ph. (1989). Role of protein kinase C activators and inhibitors, calmodulin antagonists and membrane sialic acids in polyamine transport in murine leukemia cells.  Cell Mol. Biol.  35 : 215 - 224.

13.    Moulinoux, J.Ph., Quemener, V. Khan, N.A. and  Delcros, J.-G. (1989).  Spermidine uptake by erythrocytes from normal and Lewis lung carcinoma grafted mice. I. In vitro  study. Anticancer Res. 9 : 1057 - 1062.

14.    Moulinoux, J.Ph., Quemener, V. Khan, N.A. and C. Martin (1989). Spermidine uptake by erythrocytes from normal and Lewis lung carcinoma grafted mice. II. In vivo  study.  Anticancer Res. 9 : 1063 - 1068.

15.    Khan, N.A. (1989). Idiotypic vaccination in the treatment of mice bearing B - cell lymphoma. In Vivo. 3 : 117 - 120.

16.    Khan, N.A. and Sotelo J. (1989). Heat shock stress is deleterious to CNS cultured neurons microinjected with anti - hsp 70 antibody. Biol. Cell.  65 : 199 - 202.

17.    Khan, N.A., Masson, I., Darcel, F., Quemener V., J.-F. Labarre  and Moulinoux, J.Ph. (1989). Transport mechanism of DIAM 3, a new anticancer drug, in human glioblastoma cells in culture. Biochem. Pharmacol.  39 : 2057 - 2060.

18.    Khan, N.A. and Sotelo J. (1989). Presentation of a membrane cysticercus antigen and its homology with excretory - secretory antigen. Acta Leidencia. 57 : 160 - 167.

19.    Khan, N.A., Masson, I., Quemener, V. and Moulinoux, J.-Ph. (1990). Coupling of Na+ with spermidine transporter protein in NIH Balb/c 3T3 cells. Cell Mol. Biol. 36 : 345 - 348.

20.    Khan, N.A. (1990). C1q - ELISA for detection of immune complexes. Clin. Biochim. 14 : 373 - 375.

21.    Khan, N.A., Quemener V., Seiler, N. and Moulinoux, J.Ph. (1990). Mechanism of spermidine transport and its interference with polyamine analogues in cultured mammalian cells. Pathobiol.  58 : 172 - 178.

22.    Khan, N.A., Quemener, V., R. Havouis,  and Moulinoux, J.-Ph. (1990). Mechanism of polyamine spermidine transport in Xenopus laevis  oocytes. Biochem. Int.  21 : 607 - 613.

23.    Khan, N.A., Masson, I., Quemener, V. Clari  G., Moret V.  and Moulinoux, J.Ph. (1990). Polyamines and polyamino acids regulation of protein tyrosine kinase from human erythrocytes. Biochem. Int. 20 : 863 - 868.

24.    Quemener, V., Khan, N.A. and Moulinoux, J.-Ph. (1990). Polyamines and cancer. Cancer J.  3 : 45 - 52.

25.    Khan, N.A., Quemener, V. and Moulinoux, J.Ph. (1990). Spermidine binding sites at the cell surface of normal and desialated human erythrocytes. Biochem. Arch. 5 : 321 - 329.

26.    Khan, N.A., Quemener, V. and Moulinoux, J.Ph. (1990). Inhibition of adenylate cyclase activity by polyamines in human erythrocyte plasma membranes. Life Sci. 46 : 43 - 47.

27.    Moulinoux., J.-Ph., Quemener, V., Ollitrault, J., Khan, N.A., Havouis, R., Ramée, M.- P., Leguerrier,  A., Riox, C. and Logeais, Y. (1990). Red  blood  cell  polyamine level changes following heart transplantation in man. Life. Sci.  47 : 439 - 445.

28.    Khan, N.A., Quemener, V. and Moulinoux, J.-Ph. (1990). Polyamine binding sites in the rat brain hippocampus plasma membranes : MK 801 does not influence the binding process. Membrane Biochem. 9 :  163 - 169.

29.    Khan, N.A., Quemener, V. and Moulinoux, J.-Ph. (1990). Phorbol esters increase polyamine transport without protein kinase C activation. Biochem. Pharmacol.  40 : R1-R4.

30.    Khan, N.A., and Sotelo, J. (1991). Immunocytochemical localization of the cysticercus antigen. Neurosci. Res. Commun.  9 : 9 - 12.

31.    Khan, N.A., Quemener, V. and Moulinoux, J.-Ph. (1991). Polyamine membrane transport regulation.
        Cell Biol. Int. Rep.  15 : 9 - 24.

32.    Quemener, V., Moulinoux, J.-Ph. and Khan, N.A., (1991). Biological significance of circulating polyamines in oncology. Cell Mol. Biol.  37 : 773 - 783.

33.    Khan, N.A., Quemener, V. and Moulinoux, J.-Ph. (1991). Exogeneous diacylglycerols downregulate the activity of Na+-K+-ATPase in Xenopus laevis oocytes. Exp. Cell. Res.  194 : 248 - 251.

34.    Quemener, V., Moulinoux, J.-Ph., Khan, N.A., and Seiler, N. (1991). Effects of a series of a, w-diethyl aminoalkanes on cell proliferation and binding and uptake of putrescine in human glioblastoma cell line (U 251)  in culture. Biol. Cell.  70 : 133 - 137.

35.    Khan, N.A., Quemener, V. and Moulinoux, J.-Ph. (1991). Les mécanismes régulateurs du transport transmembranaire des polyamines chez les eucaryotes. In, "Polyamines : Chemistry, Biology and Medicine" Flammarion Médecine/Science Book Series, Paris (France), pp 155 - 163.

36.    Khan, N.A., Quemener, V., Kado, R. and Moulinoux, J.-Ph. (1991). Mechanism of polyamine transport : Different actions of spermidine and methyl (glyoxal) bis - (guanylhydrazone) in Xenopus laevis  oocyte plasma membranes. In, Life Chemistry Reports,  Eds. J.V. Bannister and A.M. Michelson, Harwood Academic Publishers, U.K.,  vol. 9,  pp 231 - 237.

37.    Khan, N.A., Quemener, V. and Moulinoux, J.-Ph. (1992). Protein kinase C inhibitor (H-7) potentiates the antiproliferative effects of a polyamine biosynthesis inhibitor. Anticancer Res. 12 : 1223 - 1226.

38.    Khan, N.A., Quemener, V. and Moulinoux, J.-Ph. (1992). Phorbol esters increase polyamine transport by stimulating the Na+-K+ pump activity in murine leukemia cells. Exp. Cell  Res. 199 : 378 - 382.

39.    Khan, N.A., N. Wiernsperger, Quemener, V., R. Havouis and Moulinoux, J.-Ph. (1992). Characterization of metformin transport system in 3T3 cells. J. Cell. Physiol.  152 : 310 - 316.

40.    Khan, N.A., Quemener, V. and Moulinoux, J.-Ph. (1992). Polyamine transport and second messenger cascades. In, Life Chemistry Reports, Eds. J.V. Bannister and A.M. Michelson, Harwood Academic Publishers, U.K.,  vol. 10, pp 123 - 132.

41.    Quemener, V., Moulinoux, J.-Ph., Lucas, J., Khan, N.A.,  darcel, F., Martin, L.A., Primault, R. and Seiler, N. (1993). The effects of structural analogues of putrescine on proliferation, morphology and karyotype of glioblastoma cells in culture. Biol. Cell. 77 : 195-199.

42.    Khan, N.A., Sezan, A., Quemener, V. and Moulinoux, J.-Ph. (1993). Polyamine transport regulation by calcium and calmodulin : Role of Ca2+-ATPase.  J. Cell. Physiol.  157 : 493 - 501.

43.    Khan, N.A., Fardel, O., Havouis, R., Moulinoux, J.-Ph. and Fauchet, R. (1994). Transport of polyamines in the wild and multidrug resistance human leukemia (K 562) cells. Leukemia Res.  18 : 283 - 291.

44.    Khan, N.A., Quemener, V. and Moulinoux, J.-Ph. (1994). Characterization of polyamine transport pathways. In, Neuropharmacology of Polyamines, Ed. C. Carter. Academic Press, U.K., pp 37 - 60. "Commissioned article".

45.    Khan, N.A., N. Wiernsperger, Quemener, V. and Moulinoux, J.-Ph. (1994). Internalization of metformin is necessary to potentiate the insulin-induced Xenopus laevis oocyte maturation. J. Endocrinol. 142 : 245 - 250.

46.    Taysse, L., Troutaud, D., Khan, N.A. and Deschaux, P. (1995). Structure activity relationship of phenolic compounds (phenol, pyrocatechol  and hydroquinone) on natural lymphocytotoxicity of carp (Cyprinus carpio). Toxicology   98 : 207 - 214.

47.    Shacoori, V., Khan, N.A., Saïag, B. and Rault, B. (1995). Rat pineal cell aggregates : ultrastructural and functional charateristics. Brain. Res. Bull. 38 : 215 - 220.

48.    Khan, N.A., Shacoori, V., Havouis, R., Querné, D., Moulinoux, J.-Ph. and Rault, B. (1995). Three dimensional culture of pineal aggregates : a model of cell-cell cooperation. J. Neuroendocrinol. 7 : 353 - 359.

49.    Khan, N.A., Sezan, A., Rossignol, B. and Moulinoux, J.-Ph. (1995). Actions of growth factors on calcium signalling : different effects of phorbol esters and diacylglycerol. Biochem. Arch. 11 : 171 - 177.

50.    Taysse, L., Troutaud, D., Khan, N.A. and Deschaux, P. (1995). Structure activity relationship of phenolic compounds (phenol, pyrocatechol  and hydroquinone) on natural lymphocytotoxicity of carp (Cyprinus carpio). Toxicology   98 : 207 - 214.

51.    Deschaux, P. and Khan, N.A. (1995). Immunophysiology : The immune system as a multifunctional physiological unit. Cell. Mol. Biol. Res. 41 : 1 - 10.

52.    Betoulle, S., Troutaud, D., Khan, N.A. and Deschaux, P. (1995). Antibody response, cortisol and prolactin levels in rainbow trout. C. R. Acad. Sci. / Life Sci. (Paris). 318 : 677 - 681.

53.    Quemener, V., Havouis, R., Khan, N.A., Martin, C., Bouet, F. and Moulinoux, J.-Ph. (1995). Determination of erythrocyte polyamines as a predictive method in tumor diagnosis : An animal study with chemically induced tumors.  Anticancer Res. 15 : 2517 - 2522.

54.    Khan, N.A., Ferrière, F. and Deschaux, P. (1995). Serotonin - induced calcium signalling via 5-HT1A  receptors in human leukemia (K 562) cells. Cell. Immunol.  165 : 148 - 152.

55.    Ferrière, F., Khan, N.A.  and Deschaux, P. (1996). Mitogen-induced stimulation of fish lymphocyte proliferation via 5-HT1A receptors. Dev. Comp. Immunol. 20 : 273 - 283.

56.    Khan, N.A., Troutaud, D. and Deschaux, P. (1996). Characterization of serotonin receptors in fish brain : modulation by polyamines. Neurosci. Res. Commun. 18 : 97 - 105.

57.    Khan, N.A., Meyniel, J.-Ph. and Deschaux, P. (1996). Ca2+/calmodulin and protein kinase C regulation of serotonin transport in human K 562 lymphocytes. Cell. Immunol.  172 : 269 - 274.

58.    Khan, N.A., Moulinoux, J.-Ph. and Deschaux, P. (1996). Putrescine modulation of depolarization-induced 5-HT release from fish brain synaptosomes. Neurosci. Lett.  212 : 45 - 48.

59.    Deschaux, P. and Khan, N.A. (1997). Impact of aquatic pollution on immunophysiological interrelationships in fish. In, Ecotoxicology, Ed. J. Stolen. SOS Publication, Fair Heaven, New York, USA, pp 151 - 170.

60.    Ferrière, F., Khan, N.A., Meyniel, J. P. and Deschaux, P. (1997). Serotonin induced calcium-channel gating in rainbow trout (Oncorhynchus Mykiss) peripheral blood lymphocytes. Biochem. J.  323 : 251 -258.

61.    Meyniel, J. P., Khan, N.A., Ferrière, F. and Deschaux, P. (1997). Identification of lymphocyte 5-HT3 receptor subtype and its implication in fish T-cell proliferation. Immunol. Lett.  55 : 151 - 160.

62.    Khan, N.A. and Deschaux, P. (1997). Serotonin immunomodulation in fish J. Exp. Biol. 200 : 1833 -1838.

63.    Meyniel, J.-Ph., Khan, N.A.,  Ferrière, F. and Deschaux, P. (1998). The pharamacological profile of fish lymphocyte 5-HT3 receptor. Biochem. Arch. 14 : 11 - 122.

64.    Ferrière, F. Khan, N.A.,  Meyniel, J.-Ph. and Deschaux, P. (1999). Characterization of serotonin transport mechanismses in fish lymphocytes. Dev. Com. Immunol.  23 : 37 - 50.

65.    Khan, N.A. and Poisson, J.P. (1999). Characterization of 5-HT3 receptor-channel in human T-cells. 5-HT3 Receptor-Channels Coupled with Na+ Influx in human T-Cells : Role in T-Cell Activation. J. Neuroimmunol. 99 : 53 - 60.

66.    Khan, N.A. and Hichami, A. (1999). Ionotropic 5-hydroxytryptamine type 3 receptor is implicated in the activation of protein kinase C-dependent phospholipase D pathway in human T-cells. Biochem. J. 344 : 199 - 204.

67.    Bonin, A. and Khan, N.A. (2000). Regulation of calcium signalling by docosahexaenoic acid in human T- cells : implication of CRAC channels. J. Lipid Res. 41 : 277 - 284.

68.    Denys, A., Hichami, A.,  Maume, B., Khan, N.A. (2001). Docosahexaenoic acid modulates phorbol ester-induced activation of extracellular signal-regulated kinases 1 and 2 in NIH/3T3 cells. Lipids 36 : 813 - 818.

69.    Triboulot, C. Hichami, A. Denys, A. and Khan, N. A. (2001). w-3 dietary polyunsaturated fatty acids  diminish hypertension : implication of  T-cell signaling mechanisms. J. Nutr. 131 : 2364 - 2369.

70.    Denys, A., Hichami, A. and Khan, N. A. (2001). Eicosapentaenoic acid and docosahexaenoic acid modulate MAP kinase (ERK1/ERK2) signalling in human T-cells. J. Lipid Res. 42 : 2015 - 2020.

71.    Madani, S., Hichami, A.,  Legrand, A., Belleville, J. and Khan, N. A. (2001). Implication of Acyl Chain of Diacylglycerols in Activation of Different Isoforms of Protein Kinase C. FASEB J. 15 : 2595 - 2601.

72.    Khan, N.A. and Hichami, A. (2002). Role of n-3 Polyunsaturated Fatty Acids in the Modulation of T-Cell Signalling. In, Recent Advances in Research in Lipids. Ed. G. Pandali, Transworld Publications, USA vol. 6,  pp 65 - 78.  

73.    Denys, A., Hichami, A. and Khan, N.A. (2002). Eicosapentaenoic acid and docosahexaenoic acid modulate MAP kinase enzyme activity in human T-cells. Mol. Cell. Biochem. 232 : 143 - 148.


74.    Tessier, C., Hichami A. and Khan, N. A. (2002). Implication of three isoforms of PLA2 in human T-cell proliferation. FEBS Lett. 520 : 111 - 116.

75.    Hichami, A., Joshi, B., Simonin, A.-M. and Khan, N. A. (2002). Role of three isoforms of phospholipase A2 in capacitative calcium influx in human T-cells. Eur. J. Biochem. 269 : 5557 - 5563.

76.    Merzouk, H., Madani, S., Hichami, A., Prost, J., Belleville, J. and Khan, N.A. (2002). Age related changes in fatty acid composition of liver and serum very low density lipoprotein lipids in obese offspring of streptozotocin-induced diabetic rats. Obes.  Res.  10 : 703 - 714.

77.    Merzouk, H., Madani, S., Hichami, A., Prost, J., Belleville, J., Moutairou, K.  and Khan N. A. (2002). Impaired Lipoprotein Metabolism in Obese Offspring of  Streptozotocin-Induced Diabetic Rats. Lipids 37 : 773 - 781.

78.    Merzouk S., Hichami, A., Madani, S., Merzouk, H., Berrouiguat, A., Prost, J., Chabane-Sari, N. Moutairou, K. and Khan N. A. (2003). Antioxidant status and levels of different vitamins determined byhigh performance liquid chromatography in diabetic subjects with multiple complications. Gen. Physiol. Biophys. 22 : 15 - 27.

79.    Merzouk, H.  and Khan N. A.   (2003). Implication of lipids in macrosomia of diabetic pregnancy : can n-3 polyunsaturated fatty acids exert beneficial effects ? Clin.  Sci. 105 : 519 - 529.

80.    Aires, V., Adote, S., Hichami, A., Moutairou, K.,. Boustani E. and Khan N. A. (2003). Modulation of intracellular calcium concentrations and T-cell activation by prickly pear polyphenols. Mol. Cell. Biochem. 260 : 103-110.

81.    Aires V., Hichami, A., Moutairou, K.  and Khan N. A.  (2003). Docosahexaenoic acid  and other fatty acids induce a decrease in pHi in human T-lymphocytes. Br. J. Pharmacol. 140 : 1217 - 1226.

82.    Pédrono, F., Khan N. A. and Legrand, A. (2004). 1-O-alkylglycerols induce calcium influx in human T- lymphocytes. Life Sci.  74: 2793-2801..


83.    Madani, S., Hichami, A., Charkaoui-Malki, M. and Khan, N. A. (2004). Diacylglycerols-containing omega 3 and omega 6 fatty acids bind to RasGRP and modulate MAP kinase activation. J. Biol. Chem. 279 : 1176 - 1183.

84.    Merzouk S., Hichami A., Sari, S., Madani, S., Merzouk, H., Berrouiguet, A.Y., Chabane-Sari, N. and Khan, N.A. (2004). Impaired oxidant/antioxidant status and LDL-fatty acid composition are associated with increased susceptibility to peroxidation of LDL in diabetic patients.
Gen. Physiol. Biophys. 23:387-99.

85.    Denys, A., Aires, A., Hichami, A., Khan, N.A. (2004). Thapsigargin phosphorylates MAP kinases by opening CRAC channels and PLD activation : Inhibitory action of docosahexaenoic acid.
FEBS Lett. 564 : 177 – 182.

86.    Guermouche, B., Yessoufou A.,  Soulaimann N., Hichami, A., Moutairou K., Merzouk, H., Khan, N.A. (2004). N-3 fatty acids modulate T-cell activation in obese macrosomic rats. Obesity Res. 12:1744-53.

87.    Denys A, Hichami A, Khan NA.  (2005) n-3 PUFAs modulate T-cell activation via protein kinase C-alpha and -epsilon and the NF-kappaB signaling pathway. J Lipid Res. 46:752-8.

88. Soulimane-Mokhtari N, Guermouche B, Yessoufou A, Saker M, Moutairou K, Hichami A, Merzouk H, Khan N.A. (2005) Modulation of lipid metabolism by (N-3) PUFA in gestational diabetic rats and their macrosomic offspring. Clin Sci (Lond)109:287-95.

89.    Hichami A, Morin C, Rousseau E, Khan NA. (2005) Diacylglycerol-containing Docosahexaenoic Acid in Acyl Chain Modulates Airway Smooth Muscle Tone. Am J Respir Cell Mol. 33:378-386

90.    Yessoufou A.,  Soulaimane N., Merzouk S., Moutairou K., Ahissou H., Prost, J., Simonin A.-M., Hichami A. and Khan, N.A.  (2005). N-3 Fatty acids modulate antioxidant status in diabetic rats and their macrosomic offspring. Int.  J.  Obesity 30:739-50.

91.    Yessoufou A, Moutairou K, Girard A, Fatoke M, Prost J, Ahissou H, Djrolo F, Avode G, Amoussou-Guenou D, Hichami A, Khan NA. (2005). Antioxidant status in alcohol-related diabetes mellitus in Beninese subjects. Cell Mol Biol, 51 Suppl:OL849-58.

92.    Khan NA, Yessoufou A, Kim M, Hichami A. (2006). N-3 fatty acids modulate Th1 and Th2 dichotomy in diabetic pregnancy and macrosomia. J Autoimmun. 26:268-77.

93.    Joshi B, Khedouci S, Dagur PK, Hichami A, Sengupta U, Khan NA. (2006). On cell signalling mechanism of Mycobaterium leprae soluble antigen (MLSA) in Jurkat T cells. Mol Cell Biochem. 287:157-64. IF : 1.76

94.    Yessoufou A, Hichami A, Besnard P, Moutairou K, Khan NA. (2006). Peroxisome proliferator-activated receptor alpha deficiency increases the risk of maternal abortion and neonatal mortality in murine pregnancy with or without diabetes mellitus: Modulation of T cell differentiation.
Endocrinology. 147:4410-8.

95.    Ategbo JM, Grissa O, Yessoufou A, Hichami A, Dramane KL, Moutairou K, Miled A, Grissa A, Jerbi M, Tabka Z, Khan NA. (2006). Modulation of adipokines and cytokines in gestational diabetes and macrosomia. J Clin Endocrinol Metab. 91:4137-43

96.    Khan NA, Nishimura K, Aires V, Yamashita T, Oaxaca-Castillo D, Kashiwagi K, Igarashi K. (2006). Docosahexaenoic acid inhibits growth of mouse mammary cancer cells by interfering with p27/kip1, Cdk2, ERK1/ERK2 and retinoblastoma phosphorylation. J Lipid Res.  47:2306-2313. 

97.    Yessoufou A, Ategbo JM, Girard A, Prost J, Dramane KL, Moutairou K, Hichami A, Khan NA. (2006). Cassava-enriched diet is not diabetogenic rather it aggravates diabetes in rats. Fundam Clin Pharmacol. 20:579-586.

98.    Khan NA (2006). Immunité & Inflammation. Oléagineux Corps-gras Lipides 5 : 343-351 (Invited article)

99.      Aires V, Hichami A, Boulay G, Khan NA (2007). Activation of TRPC6 calcium channels by diacylglycerol (DAG)-containing arachidonic acid: a comparative study with DAG-containing docosahexaenoic acid. Biochimie, 89:926-37

100. Khan NA (2007). Role of lipids in macrosomia of diabetic pregnancy. Cell Biochem & Biophys. 48:79-88.

101. Aribi M., Moulessehoul S., Kendouci-Tani M., Benabadji A.B., Hichami A. and Khan N. A.  (2007). Relationship between interleukin-1β and lipids in type 1 diabetic patients. Med. Sci. Monitor 13:CR372-8.

102. Grissa O., Atègbo J.M., Yessoufou A., Tabka Z., Miled A., Jerbi M., Dramane K.L.,  Moutairou K., Prost J., Hichami A., Khan N.A. (2007). Antioxidant Status and Circulating Lipids are altered in Human Gestational Diabetes and Macrosomia. Translat. Res. 150:164-71.

103.Khan N.A. (2007). Role of T-cell cytokines in diabetic pregnancy and macrosomia. Ind. J. Biochem. Biophys. 44:344-9. Invited article

104.Aires V, Hichami A, Filomenko R, Rébé C., Bettaieb A, Khan NA (2007). DHA induces increases in [Ca2+]i by activating phosphatidylserine binding site:implication in apoptosis in  U937 cells.  Mol. Pharmacology 72: 1545-1556.

105.Hichami A, Datiche F, Ullah S, Liénard F, Chardigny JM, Cattarelli M, Khan NA. (2007). Olfactory discrimination ability and brain expression of c-fos, Gir and Glut1 mRNA are altered in n-3 fatty acid-depleted rats. Behav Brain Res. 184:1-10.

106.Khan NA, Gaillard D, El-Yassimi A, Passilly-Degrace P, Hichami A, Besnard P. (2008).Unraveling the downstream signalling of gustatory perception of lipids. Med Sci (Paris). 24:692-3.

107.Soulimane-Mokhtari NA, Guermouche B, Saker M, Merzouk S, Merzouk H, Hichami A, Madani S, Khan NA, Prost J (2008). Serum lipoprotein composition, lecithin cholesterol acyltransferase and tissue lipase activities in pregnant diabetic rats and their offspring receiving enriched n-3 PUFA diet. Gen Physiol Biophys. 27:3-11.

108.Merzouk SA, Saker M, Reguig KB, Soulimane N, Merzouk H, Guermouche B, Berrouiguet AY, Hichami A, Narce M, Khan NA. (2008).. N-3 Polyunsaturated Fatty Acids Modulate In-Vitro T Cell Function in Type I Diabetic Patients. Lipids. 43:485-97.

109. Khan, NA. and Besnard, P. (2008). Sensing of Lipids via receptor signalling in taste buds. Eur. J. Lipid Sci. Technol. 110:379-380.

110. El-Yassimi A, Hichami A, Besnard P, Khan NA. (2008). Linoleic acid induces calcium signaling, Src kinase phosphorylation, and neurotransmitter release in mouse CD36-positive gustatory cells. J Biol Chem. 283:12949-59.

111. Yessoufou A, Ategbo JM, Moutairou K, Khan NA. (2008). Malnutrition-modulated diabetes mellitus (MMDM) : a sate of review. Int. J. Biol. Chem. Sci. 2: 230-238.

112. Gaillard D, Laugerette F, Darcel N, El-Yassimi A, Passilly-Degrace P, Hichami A, Khan NA, Montmayeur JP, Besnard P. (2008). The gustatory pathway is involved in CD36-mediated orosensory perception of long-chain fatty acids in the mouse. FASEB J. 22:1458-68.

113. Yessoufou A, Atègbo JM, Attakpa E, Hichami A, Moutairou K, Dramane KL, Khan NA. (2009). Peroxisome proliferator-activated receptor-alpha modulates insulin gene transcription factors and inflammation in adipose tissues in mice. Mol Cell Biochem. 323:101-11

114. Khan NA, Besnard P (2009). Oro-sensory perception of dietary lipids: new insights into the fat taste transduction. Biochem. Biophys. Acta 1791 :149155.

115.Yessoufou A, Plé A, Moutairou K, Hichami A, Khan NA. (2009). DHA reduces suppressive and migratory functions of Treg cells. J Lipid Res. 50:2377-88

116.Attakpa E, Hichami A, Simonin AM, Sansón EG, Dramane KL, Khan NA. (2009). Docosahexaenoic acid modulates the expression of T-bet and GATA-3 transcription factors, independently of PPARalpha, through suppression of MAP kinase activation. Biochimie. 91:1359-65.

117.Khan N.A. (2010). Polyunsaturated fatty acids in the modulation of T-cell signalling. Prost. Leuk. Ess. Fatty Acids. 82:179-187. Invited article


118.Kim W, Khan NA, McMurray DN, Prior IA, Wang N, Chapkin RS. (2010). Regulatory activity of polyunsaturated fatty acids in T-cell signaling. Prog Lipid Res. 49:250-261.


119. Dagur PK, Sharma B, Kumar G, Khan NA, Katoch VM, Sengupta U, Joshi B. (2010). Mycobacterial antigen(s) induce anergy by altering TCR- and TCR/CD28-induced signalling events: insights into T-cell unresponsiveness in leprosy. Mol Immunol. 47:943-952.

120.Yessoufou A., Atègbo  J.-M., Moutairou K., Dramane K.L., Khan N.A. (2010). Physiological and immunological modulation in gestational diabetes and macrosomia: implication of in utero programming and new concept of “metabolic memory” Méd. Maladies Métab. 4: 1-7.

121. Grissa O, Yessoufou A, Mrisak I, Hichami A, Amoussou-Guenou D, Grissa A, Djrolo F, Moutairou K, Miled A, Khairi H, Zaouali M, Bougmiza I, Zbidi A, Tabka Z, Khan NA. (2010). Growth factor concentrations and their placental mRNA expression are modulated in gestational diabetes mellitus: possible interactions with macrosomia. BMC Pregnancy Childbirth. 10:7., 1471-2393/10/7

122.Yessoufou A, Moutairou K, Khan NA (2011). A model of insulin resistance in mice, born to diabetic pregnancy, is associated with alterations of transcription-related genes in pancreas and epididymal adipose tissue. J Obes. 2011;2011. pii: 654967.

123.Benammar C, Hichami A, Yessoufou A, Simonin AM, Belarbi M, Allali H, Khan NA (2010). Zizyphus lotus L. (Desf.) modulates antioxidant activity and human T-cell proliferation. BMC Complement Altern Med. 2010 Sep 24;10:54.

124.Dramane G., Akpona S.,  Simonin A. M., Besnard P., Khan N.A. (2011) Cell signaling mechanisms of gustatory perception of lipids:  can the taste cells be the target of anti-obesity agents? Curr Med. Chem. 18:3417-22.

125.Carrillo CP, Hichami A., Andreoletti P., Cherkaoui-Malki M., del Mar Cavia M., Abdoul-Azize S., Alonso-Torre S., Khan N.A (2012). Diacylglycerol-containing oleic acid induces increases in [Ca2+]i via TRPC3/6 channels in human T-cells. Biochem Biophys Acta 1821:618-626. IF :5.08;

126.Dramane G., Abdoul-Azize S., Hichami A., Vögtle, T., Akpona S., Chouabe C.,  Sadou H., Nieswandt B., Philippe Besnard P,. Khan N.A. (2012). STIM1 regulates PLA2- and Orai1/3-mediated Ca2+ signaling in CD36-positive taste bud cells and fat preference in mice. J Clin. Invest. 122:2267-82.

127.Dagur PK, Sharma B, Upadhyay R, Dua B, Rizvi A, Khan NA, Katoch VM, Sengupta U, Joshi B. (2012). Phenolic-glycolipid-1 and lipoarabinomannan preferentially modulate TCR- and CD28-triggered proximal biochemical events, leading to T-cell unresponsiveness in mycobacterial diseases. Lipids Health Dis.;11:119. doi: 10.1186/1476-511X-11-119.

128.Serý O, Sramkova T, Klempova J, Stastny F, Lochman J, Khan NA. (2012). The relationship between the C677T polymorphism of the MTHFR gene and serum levels of luteinizing hormone in males with erectile dysfunction. Neuro Endocrinol Lett. 33:499-504.

129.Abdoul-Azize S., Bendahmane, M, Hichami A, Yessoufou A, Simonin AM, Benammar C, Belarbi M, Khan NA (2013). Zizyphus lotus L. (Desf.) polyphenols modulate T-cell signaling and proliferation. Int. Immunopharmacol.  15:364-71.

130.Abdoul-Azize S., Dramane G., Subramainum, S. Simonin, AM, Khan N.A. (2012). STIM1 is indispensable for the lingual CD36-mediated calcium signaling and spontaneous fat preference in mice. Med/Sci 28:1053-5.

131.Yessoufou A, Gbenou J, Grissa O, Hichami A, Simonin AM, Tabka Z, Moudachirou M, Moutairou K, Khan NA. (2013). Anti-hyperglycemic effects of three medicinal plants in diabetic pregnancy: modulation of T cell proliferation. BMC Complement Altern Med. ;13:77.

132.Abdoul-Azize S, Selvakumar S, Sadou H, Besnard P, Khan NA. (2013). Ca2+ signaling in taste bud cells and spontaneous preference for fat: Unresolved roles of CD36 and GPR120. Biochimie. 96 :8-13.

133.Chevrot M, Bernard A, Ancel D, Buttet M, Martin C, Abdoul-Azize S, Merlin JF, Poirier H, Niot I, Khan NA, Passilly-Degrace P, Besnard P. (2013). Obesity alters the gustatory perception of lipids in the mouse: plausible involvement of lingual CD36. J Lipid Res. 54:2485-94.

134.Mrizak I, Arfa A, Fekih M, Debbabi H, Bouslema A, Boumaiza I, Zaouali M, Khan NA, Tabka Z.(2013). Inflammation and impaired endothelium-dependant vasodilatation in non obese women with gestational diabetes mellitus: preliminary results. Lipids Health Dis. 2013 Jun 27;12:93.

135.Abdoul-Azize S, Atek-Mebarki F, Bitam A, Sadou H, Koceïr EA, Khan NA. (2013). Oro-Gustatory Perception of Dietary Lipids and Calcium Signaling in Taste Bud Cells Are Altered in Nutritionally Obesity-Prone Psammomys obesus. PLoS One. 2013 Aug 1;8(8):e68532.

136.Gilbertsson, T.A. and Khan, NA (2014). Cell signaling mechanisms of oro-gustatory detection of dietary fat: advances and challenges. Prog. Lipid. Res.  53:82-92. (IF:10)

137.Ozdener MH, Subramaniam S, Sundaresan S, Sery O, Hashimoto T, Asakawa Y, Besnard P, Abumrad NA, Khan NA. (2014). CD36- and GPR120-mediated Ca2+ Signaling in Human Taste Bud Cells Mediates Differential Responses to Fatty Acids and is Altered in Obese Mice. Gastroenterology. 146:995-1005. (IF : 13)


PARTICIPATION IN THE CONGRESS / CONFERENCES

1.       Khan, N.A. and Hasan S.S. Effects of morphine on brain nucleic acids and urinary metabolites in normal and stressful states of rats. Proc. 4th National Convention of Indian Society of Life Sciences. Meerut University. Le 12-14 Juin, 1982. pp 60. Inde.

2.       Khan, N.A., Joshi, B. and Gupta S.P. Role T-cells (helper / suppressor) and B-cells in bronchial asthma. Proc. Convention of Indian College of Allergy and Applied Immunology. Calcutta. Le dec., 1985. pp 30. Inde.

3.       Khan, N.A. and Chaturvedi, P.K. Effect of Ocimum sanctum  on stress induced peptic ulcers. Ann. Conference of Indian Society of Gastroenterology. Patna-Bihar. Le 23 octobre, 1985. pp 36. Inde.

4.       Khan, N.A. and Gupta S.P. Free thiol groups and labile disulfide bonds of serum IgE in subjects with bronchial asthma. Proc. 55th Ann. Meeting of SBC (I). Trivendrum-Kerala. Le dec., 1986. pp 15. Inde.

5.       Khan, N.A. and Sotelo, J. Effects of lactic acid on CNS neurons in vitro. IInd Reunion de Investigaciones del I.N.N.N. Le mai, 1987. pp 68. Mexico.

6.       Khan, N.A. and Sotelo, J. Purification and characterization of a new cysticercus antigen.XIIth Internatoinal Congress for Tropical Medicine and Malaria., Amsterdam. Eds. P.A. Kager and A.M. Polderman. Excerpta Medica Publication Series 810. Le 18-23 septembre, 1988. pp 159.  Pays-Bas.

7.       Khan, N.A. and Sotelo, J. An approach towards a vaccine production against neurocysticercosis. Modern Approaches to New Vaccines including Prevention of AIDS. Eds. R. Chanock, H.S. Ginsberg, R.A. Lerner and F. Brown. Cold Springer Harbor Labs. New York. Le 14-18 septembre, 1988. pp 87. U.S.A.

8.       Khan, N.A., Quemener V. and Moulinoux, J.Ph. (1989). Spermidine binding sites at the cell surface of normal and desialated human erythrocytes. Gordon Research Conferences, New Port, Rhode Island. Le 19-23 juin, 1989. U.S.A.

9.       Khan, N.A.,   Quemener V.  and  Moulinoux,  J.Ph.  (1989). Characterization   of   Na+ - dependent and System A independent polyamine transport in normal human erythrocytes. Proc. Int. Conf. of ISDB held in Utrech. Le 20-25 août, 1989. Pays-Bas.  Cell Diff. & Develop.  27, S 44.

10.    Khan, N.A., Quemener V.  and  Moulinoux,  J.Ph.  (1989). Role of protein kinase C activators and inhibitors, calmodulin antagonists and membrane sialic acids in polyamine transport in murine leukemia cells. Second Meeting of GEPOL, Liége. Le 20-23 septembre, 1989. Belgique. INVITATION (Oral Communication)

11.    Khan, N.A., Quemener, V., Kado, R. and Moulinoux, J.-Ph. (1990). Mechanism of polyamine transport : Different actions of spermidine and methyl (glyoxyl) bis - (guanyl - hydrazone) in Xenopus laevis  oocyte plasma membranes. Polyamines in Biology and Medicine. Le 1-3 juin, 1990. Alberè de Tenna, Italie. Italian J. Biochem. 40 : 54A - 55A.

12.    Khan, N.A., Quemener V.  and  Moulinoux,  J.Ph.  (1990). Regulatory mechanisms of polyamine transport in eukaryotes. Third Meeting of French Polyamine Group GEPOL, Le 27 - 28 september, 1990.  Rennes, France. The Cancer J.  3, pp 5.

13.    Moulinoux, J.-Ph., Quemener, V., Khan, N.A., Delcros, J.-G., Havous, R. and Martin, R. (1990). In vitro and in vivo  study of spermidine uptake by erythrocytes from normal and Lewis lung carcinoma grafted mice. Le fev.,  1990. Taos, U. S. A. J. Cell. Biochem.  14 suppl., pp 100.

14.    Khan, N.A., Quemener V. and Moulinoux,  J.Ph.  (1991). Cell signalling and Polyamine transport. "Polyamines : Clinical and Fundamental Aspects". Le 5-6 mai, 1991 Alghero - Sassari, Italie. INVITATION (Oral communication & Chairman of the session)

15.    Moulinoux, J.-Ph., Quemener, V., Khan, N.A. (1991). Biological significance of circulating polyamines in oncology. Ist World Congress of Cellular and Molecular Biology. Le 1-7 sept, 1991. Paris, France.

16.    Khan, N.A., Fardel, O., Havouis, R., Moulinoux, J.-Ph. and Fauchet, R. (1992). Transport and metabolism of polyamines in the wild and multidrug resistance human leukemia (K 562) cells. Symposium "On The Physiological Role of Polyamines". Le 25-27 juin, 1992, Montegreto Terme - Padova, Italie. INVITATION (Oral communication & Chairman of the session)

17.    Khan, N.A., Fardel, O., Havouis, R., Moulinoux, J.-Ph. and Fauchet, R. (1992). Transport and metabolism of polyamines in the wild and multidrug resistance human leukemia (K 562) cells. Fourth Meeting of French Polyamine Group GEPOL, Le 2-3 october, 1992. Part-Dieu, Lyon, France. INVITATION

18.    Khan, N.A., Sezan, A., Quemener, V. and Moulinoux, J.-Ph. (1993). Polyamine transport regulation by calcium and calmodulin : Role of Ca2+-ATPase.  11th Meeting of British Polyalmine Research Group. Le 15-16 mai, 1993. St. Mary's Hospital, London, Angleterre. INVITATION (Oral communication)

19.    Khan, N.A., Sezan, A., Quemener, V. and Moulinoux, J.-Ph. (1993). Polyamine transport regulation by calcium and calmodulin : Role of Ca2+-ATPase.  Biochemical and Clinical Aspects of Polyamines, Bologna, Le 10-11 juin, 1993. Italie. INVITATION (Oral communication)

20.    Khan, N.A., Shacoori, V., Havouis, R., Querné, D., Moulinoux, J.-Ph. and Rault, B. (1993). Three dimensional culture of pineal aggregates : a model of cell-cell cooperation. 14th Biennial Meeting of the International Society of Neurochemistry, Le 22-27 août, 1993. Montpellier, France. J. Neurochem. (1993), 61 : S31A.

21.    Khan , N.A. Réunion de "Club de Neuroimmunomodulation". Institut Pasteur. Le 11 mars, 1994, Paris, France.

22.    Khan, N.A., Ferrière, F. and Deschaux, P. (1995). Serotonin - induced calcium signalling via 5-HT1A  receptors in human leukemia (K 562) cells. Neuroimmunolgy  Meeting organized by "Société Française d'Immunologie". Le 27-28 avril, 1995, Bordeaux, France.

23.    Khan, N.A., Troutaud, D. and Deschaux, P. (1995). Characterization of serotonin receptors in fish brain : modulation by polyamines. Meeting organized by Italien Society of Biochemistry on "Polyamines in Clinic and Biology". Le 18-20 mai, 1995. Catania, Italie. INVITATION (Oral Communication)

24.    Khan, N.A. and Deschaux, P. (1995). "Biomarkers", Workshop of european task force "BIOMAR" project. Archashon, Le 7-9 dec., 1995,  Archashon, France.

25.    Khan, N.A., J.-Ph. Meyniel and Deschaux, P. (1996). 5-HT3 receptor-channels coupled with Na+ influx in human T cells : Role in T cell activation. Reunion de Société Française d'Immunologie.  Institut Pasteur. Le 27-29 nov., 1996,  Paris, France.

26.     Meyniel, J. P., Khan, N.A., Ferrière, F. and Deschaux, P. (1996). Identification of lymphocyte 5-HT3 receptor subtype and its implication in fish T-cell proliferation. Reunion de Société Française d'Immunologie.  Le 27-29 nov., 1996, Institut Pasteur, Paris, France.

27.    Ferrière, F., Khan, N.A.  and Deschaux, P. (1996). Mitogen-induced stimulation of fish lymphocyte proliferation via 5-HT1A receptors. Réunion de Société Française d'Immunologie. Institut Pasteur. Le 27-29 nov., 1996, Paris, France.

28.    Khan, N.A. and Deschaux, P. (1996). Importance of 5-HT transport and 5-HT1A receptors in the growth of human leukemia  cells. 3rd International Symposium on "Impact of cancer biotechonology on Predictive Oncology & Therapy : Diagnostic & Prognostic Indicators". Le 26-28 octobre, 1996. Nice, France. Invitation by the Editor of the "Cancer Dectection & Prevention".

29.    Khan, N.A. and Deschaux, P. (1997). Serotonergic immunomodulation via 5-HT1A and 5-HT3 recepteors in rainbow trout. 7th Congress of International Society of Developmental and on Comparative Immunology. Gloucester Point, Virginia Institute of Marine Sciences, Virginia. Le 21-25 juillet, 1997. USA. INVITATION

30.    Khan, N.A. (1997). XII Congrès National de l’Hypertension Artérielle. Palais des Congrès, Paris. Le 10- 11 décembre, 1997. France.

31.    Foucher, C., Belleville, J. and Khan, N.A. (1998). Effects of Linoleic acid on intracellular calcium concentrations in rat lymphocytes. Société de Physiologie, Lyon. Le 14 septembre, 1998. France.

32.    Vernusse A, Mazet JL, Bonin A and Khan N. A. (1999). Nutritional fatty acids modulate the phosphorylation of MAP kinases (ERK1/ERK2) in swiss 3T3 cells. Société de Physiologie, Paris. Le septembre, 13-16 1999. France.

33.    Vernusse A, Bonin A and Khan N. A. (1999).  Modulation of signalling of MAP kinases (ERK1/ERK2) by fatty acids. 40th International Conference of the Biochemistry of Lipids.  Le septembre 14-17 1999. Dijon, France. Chem. Phys Lipids 101 : 189-190.

34.    Khan, N. A., and Bonin A and Khan N. A. (1999). DHA and calcium signalling. Meeting of GERLI, Paris. Le septembre, 13-14 1999. France.

35.    Bonin A, Vernusse A, and Khan N. A. (1999). Regulation of calcium signalling by docosahexaenoic acid in human T cells : implication of CRAC channels. 40th International Conference of the Biochemistry of Lipids, Dijon. Le septembre 14-17 1999. France. Chem. Phys Lipids 101 : 189

36.    Khan N.A (2000). Role of fatty acids in T-cell signalling. 26th Annuel Congress of Indian Society of Immunology. Bombay, Inde. Le janvier 13-15 2000. INVITATION (Oral communication & Chairman of the session)

37.     A. Hichami, C. Triboulot, A. Denys et Khan N.A. (2000). Régulation de la phosphorylation des MAP kinases (ERK1/ERK2) par le calcium : Rôle de l’acide arachidonique. GERLI, Toulouse. Le  mai 8-9, 2000 France.

38.    Denys Anne, Triboulot, A., Hichami, A. and  Khan N.A. (2000). Dietary (n-3) Polyunsaturated Fatty Acids  diminish hypertension : implication of T-cell signaling mechanisms. GERLI, Toulouse. Le  mai 8-9, 2000 France.

39.    Hichami, A. Triboulot, A. Denys and  Khan N.A. (2000). Differential regulation of  MAP kinase via a PKC-dependent and -independent mechanisms. 41st International Conference of the Biochemistry of Lipids, Halle. Le septembre 14-16, 2000. Allemagne. Chem. Phys. Lipids 107 : 37-38.

40.    Khan N.A.,  Hichami, A. and Denys A. (2000). Dietary nutritional fatty acids in T-cell activation. Société de Physiologistes, Liège. Le 17-20 Septembre, 2000. Belgique. INVITATION (Oral communication) Pflügers Archiv Eur. J. Pharmacol. 440 : R247-R248.

41.    Khan, N. A. (2000). Lipides dans l’alimentation : rôle dans la modulations des pathologies. Journées Scientifiques du UNB. Le septembre 15-19, Cotonou, Bénin.

42.    Madani, S., Hichami, A.,  Legrand, A., Belleville, J. and Khan, N. A.  (2001). Acyl chain dependence of diacylglycerol-induced activation of different isoforms of protein kinase C. 69ème  Congrès de la Société de Physiologie. Montpellier, France. Pflügers Archiv Eur. J. Physiol. 442 : R102.

43.    Merzouk, H., Hichami, A., Madani, S., Simonin, A. M. and Khan N. A. (2001) Cyclosporin A, insulin and cytokines modulate T-cell activation and calcium signalling in diabetic rats. 69ème Congrès de la Société de Physiologie. Montpellier, France. Pflügers Archiv Eur. J. Physiol. 442 : R131.

44.    Triboulot, C. Hichami, A. Denys, A. and Khan, N. A. (2001). Dietary n-3 polyunsaturated fatty acids exert antihypertensive effects via cellular signalling in T-cells. 69ème Congrès de la Société de Physiologie. Montpellier, France.  Pflügers Archiv Eur. J. Physiol. 442 : R132.

45.    Madani, S., Hichami, A., Legrand, A., Belleville J. and Khan N. A. (2002). Implication of acyl chain of diacylglycerols in activation of different isoforms of protein Kinase C. GERLI. Le avril 18-19, 2002. Nantes, France.

46.    S. Merzouk, A. Hichami, S. Madani, H. Merzouk, A. Berrouigat, J. Prost, N. Chabane-Sari, Khan N. A. (2002). Antioxidant status and levels of different vitamins determined by high performance liquid chromatography in diabetic subjects with multiple complications. GERLI. Le avril 18-19, 2002. Nantes, France.

47.    Hichami, A., Joshi, B., Simonin A.M. and Khan N. A. (2002). Arachidonic acid mediates the store-operated calcium (SOC) influx in human T-cells : Role of phospholipase A2. GERLI. Le avril 18-19, 2002. Nantes, France.

48.    Denys, A. Hichami A. and N. A. Khan (2002). Dietary n-3 fatty acids influence MAP kinase pathway, transcription of IL-2 gene and translocation of NFKB in human T-cells. GERLI 18-19 avril 2002. Nantes, France.

49.    Khan N. A. (2002). Rôle des acides gras dans la signalisation cellulaire. GERLI. Le avril 18-19, 2002. Nantes, France.  INVITATION

50.    Merzouk, H., Madani, S., Hichami, A., Prost, J. and Khan, N.A. (2002). Age related changes in fatty acid composition of liver and serum very low density lipoprotein lipids in obese offspring of streptozotocin-induced diabetic rats. Pflügers Archiv European J. Physiol. 444: pp R59. Physiome 2002. Le septembre 18-20, 2002. Ste. Foy, Canada.

51.    Khan, N. A. Hichami, A., Joshi, B. and Simonin-A.M. (2002). Role of three isoforms of phospholipase A2 in capacitative calcium influx in human T-cells. Pflügers Archiv European J. Physiol. 444: pp R59. Physiome 2002 Le septembre 18-20, 2002. Ste. Foy, Canada.
       Chairman of the session

52.    Khan, N. A. (2002). Acides gras et alimentation. Université Abomey Calavi, Cotonou. Le décembre 6 - 16, 2002. Bénin

53.    Tessier, C., Hichami A. and Khan, N. A. (2002). Implication of three isoforms of PLA2 in human T-cell proliferation.  43rd International Congress on Bioscience of Lipids. Graz, Austria,  pp 79.

54.    El Boustani, E., Prost, J., Irigaray, P., Benkhalti, F., Khan, N. A., Elmodafar, C., Hichami, A., Belleville, J. and Méjean, L. (2002). Effet de la figue de barbarie sur le profil lipidique et le statut antioxydant chez le rat hypercholestérolémique. Société Française de la Nutrition. Nutr. Clin. Métabol. 16 suppl. 1, 29-45. Dijon, France.

55.    Khan, N. A. (2003). Role of fattay acids in T-cell signalling. University of Chiba. Le juillet 27. Chiba, Japon.

56.    Hichami, A., Madani, S., Charkaoui-Malki, M. and Khan, N. A. (2003). Diacylglycerols-containing omega 3 and omega 6 fatty acids bind to RasGRP and modulate MAP kinase activation. 3rd FEPS Congress. Le juin 28 à juillet 3,  2003. Nice, France.

57.    Denys, A., Hichami A. and Khan N. A. (2003). N-3 fatty acids modulate ERK1/ERK2 activation via protein kinase C-alpha and epsilon in Jurkat T-cells. 3rd FEPS Congress. Le juin 28 à juillet 3,  2003. Nice, France.

58.    Aires V., Hichami, A., Moutairou, K.  and Khan N. A.  (2003). Docosahexaenoic acid  and other fatty acids induce a decrease in pHi in human T-lymphocytes. 3rd FEPS Congress. Le juin 28 à juillet 3,  2003. Nice, France.

59.    Pédrono, F., Khan N. A. and Legrand, A. (2003). Regulation of calcium influx by 1-O-alkylglycerols in human T lymphocytes. GERLI Congres de Lipidomique.  Le septembre, 2-5, 2003. Paris, France.

60.    Khan N. A. and  Hichami, A. (2004). N-3 fatty acids modulate TH1 and TH2 differentiation in gestational diabetic and macrosomic offspring. ISSFAL meeting Juillet, Brighton, Royaume-Uni. INVITATION

61.    Guermouche, B., Akadiri Yessoufou, Nassima Soulimane, Hafida Merzouk, Kabirou Moutairou, Aziz Hichami and Khan N. A. (2005) N-3 fatty acids modulate T-cells calcium signaling in obese macrosomic rats. Communication affichée, 71è Congrès de la Société de Physiologie, Paris Bercy du 15 au 17 Septembre 2004 : « Du gène à la fonction » Paris

62.    Yessoufou, A., Soulaimann, N., Merzouk, SA., Moutairou, K., Ahissou, H., Prost, J., Simonin, A.M., Hichami, A. and Khan N. A. (2005) N-3 Fatty Acids Modulate Antioxidant Status in Diabetic Rats and Their Macrosomic Offspring. Communication affichée, 71è Congrès de la Société de Physiologie, Bercy du 15 au 17 Septembre 2004 : « Du gène à la fonction » Paris

63.    Yessoufou, A., Hichami, A.,  Moutairou, K., and N. A. Khan. (2005) PPARα in the modulation of lipid metabolism in gestational diabetes and juvenile obesity. “3rd International Symposium on « PPARS EFFICACY AND SAFETY: FROM BASIC SCIENCE TO CLINICAL APPLICATIONS» , Monte Carlo, March 19-23, 2005, Monaco,

64.    Yessoufou, A., Hichami, A.,  Ategbo, J. M., Dramane, K. L., Moutairou K. and N. A. Khan (2005): Implication de PPAR-alpha dans la modulation du métabolisme des lipides dans le diabète gestationnel et la macrosomie. 11ème Forum des Jeunes Chercheurs les 9 et 10 juin 2005 à Dijon, Ecole Doctorale Sciences de la Vie et de la Santé - Université de Bourgogne, Dijon, France.

65.    Yessoufou, A., Moutairou K., Girard, A.,  Fatoké, M.,  Prost, J.,  Ahissou, H.,  Djrolo, F., Avodé,  G., Amoussou-Guenou, D., Hichami A. and Khan, N. A. (2005) Modulation of Antioxidant Status in Alcohol-related Diabetes Mellitus in Beninese Subjects.  27 – 29 juin, 2005, 72ième  Congrès de la Société de Physiologie. Rennes, France.

66.    Hichami A and Khan N. A. (2005) Modulation of gestational diabetes and macrosomia by n-3 fatty acids.  27 – 29 juin, 200572ième  Congrès de la Société de Physiologie. Rennes, France.

67.    Ullah, S., Rialland,  M.,  Datiche, F.,  Liénard, F.,  Hichami, A.,  Chardigny, J-M,  Cattarelli M., and Khan N. A. (2005) N-3 fatty acids-deficient rats exhibit impaired acquisition of an olfactory discrimination task. 27 – 29 juin, 2005, 72ième  Congrès de la Société de Physiologie. Rennes, France.

68.    Khan N.A. (2005). Implication of lipids in diabetic pregnancy and macrosomia. 6th Annual Rachmiel Levine Diabetes & Obesity Symposium. November 9 – 12, 2005, Universal City, Los angeles, USA, INVITED SPEAKER

69.    Khan NA (2005). Diacylglyceroçls and T cell activation. 32nd Conference of Immunology Society, Chandigarh, India, Novembre 24-27. INVITATION

70.    Yessoufou A, Atègbo JM, Hichami A, Dramane KL, Moutairou K, and Khan NA. (2005). Implication de PPAR-alpha dans la modulation du métabolisme des lipides dans le diabète gestationnel et la macrosomie. 11ème Forum des Jeunes Chercheurs des 9 et 10 Juin 2005 à Dijon, Ecole Doctorale Sciences de la Vie et de la Santé-Université de Bourgogne, Dijon, France.

71.    Khan  NA. (2006). Maternal diabetes and obese offspring: Beneficial effects of omega-3 fatty acids.: 1er Congrès International de VITAGORA : Santé et Nutrition: de la Recherche à la Clinique, du 2 au 4 Mars 2006 à Dijon, France. Round-table Conference

72.    Grissa O, Atègbo JM, Kasdallah-Grissa A, Jerbi M, Miled AH, Bibi M, Khan NA and Tabka Z. (2006). Activité de la superoxide dismutase et taux des vitamines A, E et C chez les nouveau-nés macrosomiques. « Association Tunisienne des Sciences Biologiques » : 17ème Journée Biologique du 20 au 23 Mars 2006 (Hammamet,) Tunisie.

73.    Atègbo JM, Grissa O, Yessoufou A, Tabka Z, Miled AH, Moutairou K, Jerbi M, Dramane KL, Hichami A, and Khan NA. (2006). Antioxidant status and circulating lipids are altered in gestational diabetes and their macrosomic offspring. Congrès de Physiologie, de Pharmacologie et de Thérapeutique du 10 au 12 Avril 2006, Montpellier,  France.

74.    Atègbo JM, Grissa O, Yessoufou A, Hichami A, Dramane KL, Moutairou K, Miled A, Jerbi M, Tabka Z, and Khan NA. (2006). Modulation des adipokines et différenciation des cellules T au cours du diabète gestationnel et la macrosomie. XIIe Forum des Jeunes Chercheurs des 8 et 9 Juin 2006, Besançon, France.

75.    Yessoufou A, Aires V, Atègbo JM, El-Yassimi A, Plé AML, Simonin AM, Dramane KL, Moutairou K, Hichami A, and Khan NA. (2006). Omega-3 fatty acids modulate antioxidant status and T cell activation in diabetic pregnancy and obesity. 7th Congress of the International Society for the Study of Fatty acids & Lipids (ISSFAL 2006), 23-28 July 2006 at Cairus Convention Centre, Cairus, Queensland, Australia.

76.    Atègbo JM, Yessoufou A, Moutairou K, Hichami A, Dramane KL, and Khan NA. (2006). Modulation des adipokines et des cytokines au cours du diabète gestationnel et la macrosomie. 3ème Café Scientifique de l’Institut des Sciences Biomédicales Appliquées (ISBA) du 27 Octobre 2006, Cotonou, Bénin.

77.    Aires V, Hichami A, Boulay G, Khan NA (2006). Activation of TRPC6 calcium channels by diacylglycerol (DAG)-containing arachidonic acid: a comparative study with DAG-containing docosahexaenoic acid. Cell and Molecular Biology of TRP channels. University of Bath, 7-8 septembre, 2007, UK.

78.    Atègbo JM, Grissa O, Yessoufou A,  Hichami A, Dramane KL, Moutairou K, Miled A, Grissa A, Jerbi M, Tabka Z, and Khan NA. (2007). Modulation of Adipokines and Cytokines in Gestational Diabetes and Macrosomia. 33rd Indian Immunology Society Conference, Theme: Molecular and Clinical Immunology in Health and Diseases. AIIMS, 28 to 31st January, 2007, New Delhi, India.

79.    Khan  NA. (2006). Viamins & Nutrition. 2nd International Congress VITAGORA : Nutrition & Health du 7 au 9 March 2007, Dijon, France. Chairman of the session

80.    Khan N.A. (2006). Nutrition : gestational diabetes and Macrosomia. 1st International Congress of Tunisia, 10 – 13 november, 2006. Tunis, Tunisia. INVITED SPEAKER

81.    Grissa O, Atègbo JM, Miled AH, Jerbi M, Khan NA and Tabka Z. Growth Factors are altered in human gestational diabetes and their macrosomic offspring. Second International Congress of Applied Chronobiology and chronomedicine (ICACC). March 23-28, 2007, Tunis. Gammarth, Tunisia.

82.    Grissa O, Atègbo JM, Miled AH, Jerbi M, Tabka Z and Khan NA (2007).  Activity of adiponectin, leptin and cytokines in diabetic mothers and their macrosomic offspring. Communication affichée au Congrès de Physiologie, de Pharmacologie et de Thérapeutique du 11 au 13 Avril 2007, Toulouse, France.

83.    Atègbo JM, Grissa O, Yessoufou A, Hichami A, Miled A, Jerbi M, Moutairou K, Dramane KL, Tabka Z and Khan NA. (2007). Growth Factors are altered in Human Gestational Diabetes and their   Macrosomic Offspring. XIIIe Forum des Jeunes Chercheurs et BIOTechno des 14 et 15 Juin 2007, Dijon, France.

84.    Khan N.A. (2008). Immunological targets in gestational diabetes mellitus (GDM) and macrosomia. 1st International Congress of Tunisia, 16 – 20 Octobre, 2008, Yasmine-Hammamet, Tunisia. INVITED SPEAKER

85.    Khan N.A. (2008). CD36 and taste for fat. P2T. 9 – 11 avril, 2008, Clermont-Ferrand, France. INVITED SPEAKER and Chainman of the session

86.    Khan N.A. (2008). Immunomodulatiory effects of Polyphenols. 1st International Congress on Bioactive molecules.  29 - 30 mai 2008, Oujda – Morocco.

87.    Khan N.A. (2008). Nutrition, Lipids & Obesity. 12 – 15 november, 2008, Pragure, Czech Republic. INVITED SPEAKER & VLTAVA LAUREAT

88.    Khan N.A. (2009). Fatty acids and signaling in T cells. Fatty acids in cell Signalling (FACS). 13-16 July 2009, Keble College, Oxford, UK. INVITED SPEAKER

89.    Khan NA (2009). DHA in the modulation of T-reg cells. Indian Immunology Society, 16-18 December 2009. Bangalore, India. INVITED SPEAKER

90.    Khan NA (2010). Nutritional management of gestational diabetes mellitus and macrosomia. International Congress on Drug Delivery. 1 – 5 February, 2010. Dubai, INVITED SPEAKER

91.    Khan NA (2010). Dietary management of gestational daibetes mellitus and macrosomia.International meeting of IRD-Corus on Socities and Health . 13 – 16 september, 2010. Dar-es-Salaam, Tanzania,. INVITED SPEAKER and Chairman of the session

92.    Khan NA (2010). Gestational diabetes mellitus and inflammation. IRD-ISBA, Cotonou. 24  september, 2010. Cotonou, Benin. INVITED SPEAKER

93.    Khan NA (2010). A taste for fat :  cell signaling mechanisms. Brno, République Tchèque. INVITED SPEAKER

94.    Khan NA (2011). Cell signaling mechanisms of lipid gustatory perception in the mouse.Dubai Women’s college, Dubai. 3rd  International Congress on Drug Discovery, February 7-10, 2011, Dubai, INVITED SPEAKER & CHAIRMAN of a session

95.    Khan NA (2011). Deletion of PPAR-alpha gene decreases suppressive capacity of Treg cells and inhibits tumor growth in mice. 8th GERLI meeting, INSA Lyon, France. October 26-28, 2011.

96.    Khan NA (2011). Effects of fatty acids on the immune system: modulation of cell signaling. Journées Francophones de Nutrition (SFN), December 7-9, 2011, Reims, France. INVITED SPEAKER

97.    Khan NA (2012). Role of CIF and Orai1/3-mediated Ca2+ signaling in CD36-positive taste bud cells and fat preference in mice. 21st LBP Workshop, Dijon, January 26-27, 2012. France. INVITED SPEAKER

98.    Khan NA (2012). Obesity: a story of the taste. 3rd International Congress of Nutrition. 20 – 2-4 may, 2012, Yasmine-Hammamet. Tunisia. INVITED SPEAKER

99.    Khan NA (2012). Sensing of dietray lipids. Université Sciences et Technique Houari-Boumedienne, Algiers, Septembre 22-23, 2012. Algeria. INVITED SPEAKER

100.Khan NA (2012). Calcium signaling in taste bud cells and spontaneous  preference for fat. October 17-19, 2012., UPMC Paris, France. INVITED SPEAKER

101.Khan NA (2012). Mechanisms of calcium signaling in lipid oro-gustatory cells and spontaneous preference for fat. 10th International Sympodiusm on “Molecular and Neural Mechanisms of tsate and Olfactory Perception”. November 3-4, Fukuoka, Japan. INVITED SPEAKER

102.Khan NA (2013). Cell signaling in lipid gustatory cells. Monell Chamical Senses Center. February 26. Philadelphia. USA. INVITED SPEAKER

103.Khan NA (2013). Role of STIM1 in cell signaling in lipid gustatory cells. Washington University, St. Louis. February 28. St. Louis. USA. INVITED SPEAKER

104.Khan NA (2013). Lipid taste perception: advances. Masaryk University, Brno. May 10. Czech Republic. INVITED SPEAKER and Linnolec Lectureship Award.

105.Khan NA (2013). Role of PPAR-alpha in immunomodulation, 40th Annual meeting of Indian Immunology Society, New Delhi, 15-17 november 2013. India. INVITED SPEAKER

106.Khan NA (2013). Obesity: a story of taste. Ecole Supérieure de santé, Tunis. April 15. Tunisia. INVITED SPEAKER

107.Khan NA (2013). Implication of taste in obesity. Université de Tlemcen. June 10. Algeria. INVITED SPEAKER

108.Khan NA (2013). Calcium signaling in lipid taste perception. 33rd Blankenese Conferences. Hambourg. Germany, 25-29 May. INVITED SPEAKER

109.Khan NA (2014). Lipid signaling in health and diseasqe. 3rd International Congress of the Tunisian Nutritional Society, Yasmine Hammaet, Tunisia. 21-23 March. INVITED SPEAKER

110.Khan NA (2014). XIV Congress of the European Chemoreception Research Organisation (ECRO) from 10 to 13 September, 2014, Dijon, France. INVITED SPEAKER

111.Khan NA (2014). A taste for fat. Colloque International "Nutrition & Santé", 12th  to 13rd  May 2013, Constataine, Algeria. INVITED SPEAKER

112.Khan NA (2014). Fatty acids as immunomodulators. International Meeting of Comparative Immunology and Immunophysiology, 22 to 25 April, Tlemcen, Algeria. INVITED SPEAKER

113.Khan NA (2014). Fatty acids as immunomodulators. International Meeting of Comparative Immunology and Immunophysiology, 12 to 17 June, Université Ibn-Tofail, Kenitra, Morocco. INVITED SPEAKER
114.